Reverse 1999: Semmelweis Build Guide

Semmelweis is one of the new 6-star characters to be released during the Reverse: 1999 Version 1.9 update. She is a free character that players can get just by logging in during the anniversary update, and she is also a good support character that both old and new players can use to help them clear difficult content.

Discover the best builds for Semmelweis below!

Semmelweis Introduction

	Name	Semmelweis
	Rarity	6-star
	Afflatus	Mineral
	Damage Type	Reality
	Release Date	September 19, 2024

Semmelweis is a 6-star character from the Mineral Afflatus that deals Reality damage and helps the team with Crit and DMG buffs.

She buffs the team by draining their HP, but in turn making them stronger with the [Fresh Blood] buff. Semmelweis can also use an Array buff through her Ultimate. This sets up the [Blood Domain] Array, which gives allies bonus damage based on how much HP they have lost.

Due to her team's HP-draining mechanics, Semmelweis must be paired with characters who have a good amount of sustain.

Semmelweis Best Resonance

When it comes to resonance builds, Semmelweis benefits the most from an ATK-based Resonance setup. This will help her deal a bit more damage while helping out your team as a pseudo-sub-dps. Additionally, you can also run her with a crit build for more added DPS. You can find example Resonance 10 builds below!

Best

Alternative

Semmelweis Best Psychubes

Semmelweis pairs best with the 6-star [Long Night Talk] Psychube thanks to its ATK and DMG increase effects, which Semmelweis can use perfectly. If you do not happen to have it, you can also pair her with the [Knock on the Door] 6-star Psychube as an alternative.

Long Night Talk

• When the Carrier has 2 or more [Pos Status] buffs, DMG Dealt +8% when attacking.
  When the Carrier uses a Buff Incantation, gain ATK +2%, stacks up to 2 times.

Knock on the Door

• When the carrier attacks a target in the [Burn] status, DMG Dealt +6%. When the carrier's extra action is a mass attack, Incantation Might +4%.

Semmelweis Best Teams

When it comes to team, Semmelweis works best with strong DPS units that rely on Crit or can manipulate their HP to make the most of Semmelweis’ buffs. Below you can find two such example teams.

Eternity Team

Hypercarry Team
Eternity	Semmelweis	Ezra

The Eternity team features the following characters:

• Eternity
• Semmelweis
• Ezra

This team makes use of Eternity as a main DPS unit thanks to her ability to manipulate her HP and gain the most out of Semmelweis’ buff. Ezra, on the other hand, is there to offer sustain so that both Eternity and Semmelweis can do their thing reliably!

Windsong Team

Hypercarry Team
Windsong	Semmelweis	Vila

The Windsong team consists of the following characters:

• Windsong
• Semmelweis
• Vila

In this team, we focus on Windsong as the main DPS thanks to her constant damage output and reliance on Crit, which pairs well with Semmelweis’ buffs. Vila is here to add that much-needed sustain so that both Windsong and Semmelweis can remain healthy and continue dishing out damage!